Effect of spin labelling on the aggregation kinetics of yeast prion protein Ure2

Amyloid formation is involved in a wide range of neurodegenerative diseases including Alzheimer's and prion diseases. Structural understanding of the amyloid is critical to delineate the mechanism of aggregation and its pathological spreading. Site-directed spin labelling has emerged as a power...

Full description

Bibliographic Details
Main Authors: Emilie N. Liu, Giovanna Park, Junsuke Nohara, Zhefeng Guo
Format: Article
Language:English
Published: The Royal Society 2021-03-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.201747