Performance of Metagenomic Next-Generation Sequencing for the Diagnosis of Cryptococcal Meningitis in HIV-Negative Patients

Performance of Metagenomic Next-Generation Sequencing for the Diagnosis of Cryptococcal Meningitis in HIV-Negative Patients

ObjectivesMetagenomic next-generation sequencing (mNGS) has been applied more and more widely for the diagnosis of infectious diseases, but its performance in the diagnosis of cryptococcal meningitis (CM) remains unclear.MethodsCerebrospinal fluid (CSF) samples from 197 HIV-negative patients with su...

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Bibliographic Details
Main Authors: Zhouqing Gan, Jia Liu, Yijie Wang, Lu Yang, Zheng Lou, Han Xia, Min Li, Zhuolin Chen, Ying Jiang, Fuhua Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
metagenomic next-generation sequencing
cerebrospinal fluids
cryptococcal meningitis
diagnosis
Cryptococcus gattii
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.831959/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2022.831959/full

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