RET Copy Number Alteration in Medullary Thyroid Cancer Is a Rare Event Correlated with RET Somatic Mutations and High Allelic Frequency

RET Copy Number Alteration in Medullary Thyroid Cancer Is a Rare Event Correlated with RET Somatic Mutations and High Allelic Frequency

Copy number variations (CNV) of the <i>RET</i> gene have been described in 30% of Medullary Thyroid Cancer (MTC), but no information is available about their role in this tumor. This study was designed to clarify <i>RET</i> gene CNV prevalence and their potential role in MTC...

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Bibliographic Details
Main Authors: Teresa Ramone, Chiara Mulè, Raffaele Ciampi, Valeria Bottici, Virginia Cappagli, Alessandro Prete, Antonio Matrone, Paolo Piaggi, Liborio Torregrossa, Fulvio Basolo, Rossella Elisei, Cristina Romei
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Genes
Subjects:
medullary thyroid cancer
<i>RET</i>
copy number variation
MLPA
Online Access:https://www.mdpi.com/2073-4425/12/1/35

Internet

https://www.mdpi.com/2073-4425/12/1/35

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