Corticotropin releasing factor-overexpressing mouse is a model of chronic stress-induced muscle atrophy.

Chronic stress and continually high glucocorticoid levels can induce muscle atrophy. Unfortunately, there is a lack of appropriate animal models for stress-induced muscle atrophy research. Corticotropin releasing factor-overexpressing (CRF-OE) mice are a transgenic model of chronic stress that exhib...

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Bibliographic Details
Main Authors: Wesuk Kang, Tao Tong, Taesun Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0229048