Antitumor Mechanism of Metformin via Adenosine Monophosphate-activated 
Protein Kinase (AMPK) Activation

Antitumor Mechanism of Metformin via Adenosine Monophosphate-activated 
Protein Kinase (AMPK) Activation

Metformin, as a traditional oral hypoglycemic agent, is commonly used in the clinical treatment for type 2 diabetes. Recently, a large number of epidemiological researches have shown that metformin could reduce the tumor morbidity of type 2 diabetes, moreover, it has also been indicated that metform...

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Bibliographic Details
Main Authors: Zhaoyu CHEN, Liantang WANG, Yanyang CHEN
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2013-08-01
Series:Chinese Journal of Lung Cancer
Subjects:
Metformin
Antitumor mechanism
Adenosine monophosphate-activated protein kinase (AMPK)
Metabolism
Cell cycle arrest
Oxidative stress
Transformation of cancer/tumor stem cells
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2013.08.07

Internet

http://dx.doi.org/10.3779/j.issn.1009-3419.2013.08.07

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