The effects of promoter methylation on downregulation of DAZAP2 in multiple myeloma cell lines.

Our previous studies had shown that DAZAP2 was profoundly downregulated in bone marrow mononuclear cells from multiple myeloma patients. In this report, we analyzed epigenetic changes in multiple myeloma cell lines to understand the molecular mechanisms underlying the downregulation of DAZAP2. Four...

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Bibliographic Details
Main Authors: Sai-Qun Luo, Jing-Ping Hu, Qiang Qu, Jiang Li, Wei Ren, Jia-Ming Zhang, Yan Zhong, Wei-Xin Hu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3392238?pdf=render