Suppression of OCT-1 in Metastatic Breast Cancer Cells Reduces Tumor Metastatic Potential, Hypoxia Resistance, and Drug Resistance

Suppression of OCT-1 in Metastatic Breast Cancer Cells Reduces Tumor Metastatic Potential, Hypoxia Resistance, and Drug Resistance

OCT-1/POU2F1 is a ubiquitously expressed transcription factor. Its expression starts at the earliest stage of embryonic development. OCT-1 controls genes involved in the regulation of differentiation, proliferation, cell metabolism, and aging. High levels of OCT-1 transcription factor in tumor cells...

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Bibliographic Details
Main Authors: Alexander G. Stepchenko, Elizaveta V. Bulavkina, Tatiana N. Portseva, Sofia G. Georgieva, Elizaveta V. Pankratova
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Life
Subjects:
breast cancer
therapeutic targets
OCT-1 transcription factor
metastasis
drug resistance
Online Access:https://www.mdpi.com/2075-1729/12/9/1435

Internet

https://www.mdpi.com/2075-1729/12/9/1435

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