Helicobacter pylori glycan biosynthesis modulates host immune cell recognition and response

Helicobacter pylori glycan biosynthesis modulates host immune cell recognition and response

IntroductionThe pathogenic bacterium Helicobacter pylori has evolved glycan-mediated mechanisms to evade host immune defenses. This study tests the hypothesis that genetic disruption of H. pylori glycan biosynthesis alters immune recognition and response by human gastric epithelial cells and monocyt...

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Bibliographic Details
Main Authors: Katharine A. Barrett, Francis Jacob Kassama, William Surks, Andrew J. Mulholland, Karen D. Moulton, Danielle H. Dube
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
glycan
immunology
glycosylation mutant
phase variation
Helicobacter pylori
metabolic labeling
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1377077/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2024.1377077/full

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