Enhanced production of d-pantothenic acid in Corynebacterium glutamicum using an efficient CRISPR–Cpf1 genome editing method

Enhanced production of d-pantothenic acid in Corynebacterium glutamicum using an efficient CRISPR–Cpf1 genome editing method

Abstract Background Corynebacterium glutamicum has industrial track records for producing a variety of valuable products such as amino acids. Although CRISPR-based genome editing technologies have undergone immense developments in recent years, the suicide-plasmid-based approaches are still predomin...

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Bibliographic Details
Main Authors: Rui Su, Ting Wang, Taidong Bo, Ningyun Cai, Meng Yuan, Chen Wu, Hao Jiang, Huadong Peng, Ning Chen, Yanjun Li
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Microbial Cell Factories
Subjects:
Corynebacterium glutamicum
CRISPR-Cpf1
Genome editing
Vitamin
Metabolic engineering
Synthetic biology
Online Access:https://doi.org/10.1186/s12934-023-02017-1

Internet

https://doi.org/10.1186/s12934-023-02017-1

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