Human Sulfatase 2 inhibits <it>in vivo </it>tumor growth of MDA-MB-231 human breast cancer xenografts

Human Sulfatase 2 inhibits <it>in vivo </it>tumor growth of MDA-MB-231 human breast cancer xenografts

<p>Abstract</p> <p>Background</p> <p>Extracellular human sulfatases modulate growth factor signaling by alteration of the heparin/heparan sulfate proteoglycan (HSPG) 6-<it>O</it>-sulfation state. HSPGs bind to numerous growth factor ligands including fibrobl...

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Bibliographic Details
Main Authors: Peterson Sarah M, Iskenderian Andrea, Cook Lynette, Romashko Alla, Tobin Kristen, Jones Michael, Norton Angela, Gómez-Yafal Alicia, Heartlein Michael W, Concino Michael F, Liaw Lucy, Martini Paolo GV
Format: Article
Language:English
Published: BMC 2010-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/427

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http://www.biomedcentral.com/1471-2407/10/427

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