UPRmt and coordinated UPRER in type 2 diabetes

The mitochondrial unfolded protein response (UPRmt) is a molecular mechanism that maintains mitochondrial proteostasis under stress and is closely related to various metabolic diseases, such as type 2 diabetes (T2D). Similarly, the unfolded protein response of the endoplasmic reticulum (UPRER) is re...

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Bibliographic Details
Main Authors: Zhanfang Kang, Feng Chen, Wanhui Wu, Rui Liu, Tianda Chen, Fang Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.974083/full