Polyphenols from persimmon fruit attenuate acetaldehyde-induced DNA double-strand breaks by scavenging acetaldehyde

Abstract Acetaldehyde, a metabolic product of ethanol, induces DNA damage and genome instability. Accumulation of acetaldehyde due to alcohol consumption or aldehyde dehydrogenase (ALDH2) deficiency increases the risks of various types of cancers, including esophageal cancer. Although acetaldehyde c...

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Váldodahkkit: Kenichiro Matsuzaki, Kenji Kumatoriya, Mizuki Tando, Takashi Kometani, Miki Shinohara
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Nature Portfolio 2022-06-01
Ráidu:Scientific Reports
Liŋkkat:https://doi.org/10.1038/s41598-022-14374-9