In silico directed evolution of Anabas testudineus AtMP1 antimicrobial peptide to improve in vitro anticancer activity

Various studies have demonstrated that directed evolution is a powerful tool in enhancing protein properties. In this study, directed evolution was used to enhance the efficacy of synthesised Anabas testudineus AtMP1 antimicrobial peptides (AMPs) in inhibiting the proliferation of cancer cells. The...

Full description

Bibliographic Details
Main Authors: Shazrul Fazry, Ahmed Abdulkareem Najm, Ibrahim Mahmood Mahdi, Arnold Ang, LiTing Lee, Choy-Theng Loh, Sharifah Sakinah Syed Alwi, Fang Li, Douglas Law
Format: Article
Language:English
Published: PeerJ Inc. 2024-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/17894.pdf