Genetically Determined Circulating Lactase/Phlorizin Hydrolase Concentrations and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study

Genetically Determined Circulating Lactase/Phlorizin Hydrolase Concentrations and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study

Previous research has found that milk is associated with a decreased risk of colorectal cancer (CRC). However, it is unclear whether the milk digestion by the enzyme lactase-phlorizin hydrolase (LPH) plays a role in CRC susceptibility. Our study aims to investigate the direct causal relationship of...

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Bibliographic Details
Main Authors: Sihao Han, Jiemin Yao, Hajime Yamazaki, Samantha A. Streicher, Jianyu Rao, Roch A. Nianogo, Zuofeng Zhang, Brian Z. Huang
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Nutrients
Subjects:
colorectal cancer
lactase/phlorizin hydrolase
lactose non-persistence
milk digestion
Mendelian randomization
Online Access:https://www.mdpi.com/2072-6643/16/6/808

Internet

https://www.mdpi.com/2072-6643/16/6/808

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