Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses.

Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses.

Although it has recently been shown that A/J mice are highly susceptible to Staphylococcus aureus sepsis as compared to C57BL/6J, the specific genes responsible for this differential phenotype are unknown. Using chromosome substitution strains (CSS), we found that loci on chromosomes 8, 11, and 18 i...

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Bibliographic Details
Main Authors: Sun-Hee Ahn, Hitesh Deshmukh, Nicole Johnson, Lindsay G Cowell, Thomas H Rude, William K Scott, Charlotte L Nelson, Aimee K Zaas, Douglas A Marchuk, Sehoon Keum, Supaporn Lamlertthon, Batu K Sharma-Kuinkel, Gregory D Sempowski, Vance G Fowler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2932726?pdf=render

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http://europepmc.org/articles/PMC2932726?pdf=render

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