Optogenetic restoration of high sensitivity vision with bReaChES, a red-shifted channelrhodopsin

Optogenetic restoration of high sensitivity vision with bReaChES, a red-shifted channelrhodopsin

Abstract The common final pathway to blindness in many forms of retinal degeneration is the death of the light-sensitive primary retinal neurons. However, the normally light-insensitive second- and third-order neurons persist optogenetic gene therapy aims to restore sight by rendering such neurons l...

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Bibliographic Details
Main Authors: Lay Khoon Too, Weiyong Shen, Dario A. Protti, Atomu Sawatari, Dylan A. Black, Catherine A. Leamey, Jin Y. Huang, So-Ra Lee, Ashish E. Mathai, Leszek Lisowski, John Y. Lin, Mark C. Gillies, Matthew P. Simunovic
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23572-4

Internet

https://doi.org/10.1038/s41598-022-23572-4

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