Premigratory neural crest stem cells generate enteric neurons populating the mouse colon and regulating peristalsis in tissue‐engineered intestine

Abstract Hirschsprung's disease (HSCR) is a common congenital defect. It occurs when bowel colonization by neural crest‐derived enteric nervous system (ENS) precursors is incomplete during the first trimester of pregnancy. Several sources of candidate cells have been previously studied for thei...

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Bibliographic Details
Main Authors: Huipu Yuan, Hui Hu, Rui Chen, Wenbo Mu, Liangliang Wang, Ying Li, Yuelei Chen, Xiaoyan Ding, Yongmei Xi, ShanShan Mao, Mizu Jiang, Jie Chen, Yong He, Lang Wang, Yi Dong, Jinfa Tou, Wei Chen
Format: Article
Language:English
Published: Oxford University Press 2021-06-01
Series:Stem Cells Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/sctm.20-0469