Early Components of the Complement Classical Activation Pathway in Human Systemic Autoimmune Diseases

Early Components of the Complement Classical Activation Pathway in Human Systemic Autoimmune Diseases

The complement system consists of effector proteins, regulators, and receptors that participate in host defense against pathogens. Activation of the complement system, via the classical pathway (CP), has long been recognized in immune complex-mediated tissue injury, most notably systemic lupus eryth...

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Bibliographic Details
Main Authors: Katherine eLintner, Yee Ling eWu, Yan eYang, Charles eSpencer, Georges eHauptmann, Lee eHebert, John eAtkinson, Chack-Yung eYu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Immunology
Subjects:
Autoimmune Diseases
Complement C1q
Complement C1r
Complement C1s
Complement C2
Complement C4
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00036/full

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http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00036/full

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