Escherichia coli resistance mechanism AcrAB-TolC efflux pump interactions with commonly used antibiotics: a molecular dynamics study

Abstract While antibiotic resistance poses a threat from both Gram-positive bacteria (GPB) and Gram-negative bacteria (GNB), GNB pose a more imminent public health hazard globally. GNB are a threat to growing antibiotic resistance because of the complex makeup of the membrane. The AcrAB-TolC efflux...

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Bibliografske podrobnosti
Main Authors: Brooke L. Smith, Sandun Fernando, Maria D. King
Format: Article
Jezik:English
Izdano: Nature Portfolio 2024-02-01
Serija:Scientific Reports
Online dostop:https://doi.org/10.1038/s41598-024-52536-z