Targeting Protein-Protein Interactions to Inhibit Cyclin-Dependent Kinases
Cyclin-dependent kinases (CDKs) play diverse and critical roles in normal cells and may be exploited as targets in cancer therapeutic strategies. CDK4 inhibitors are currently approved for treatment in advanced breast cancer. This success has led to continued pursuit of targeting other CDKs. One cha...
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Format: | Article |
Language: | English |
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MDPI AG
2023-03-01
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Series: | Pharmaceuticals |
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Online Access: | https://www.mdpi.com/1424-8247/16/4/519 |