Targeting Protein-Protein Interactions to Inhibit Cyclin-Dependent Kinases

Targeting Protein-Protein Interactions to Inhibit Cyclin-Dependent Kinases

Cyclin-dependent kinases (CDKs) play diverse and critical roles in normal cells and may be exploited as targets in cancer therapeutic strategies. CDK4 inhibitors are currently approved for treatment in advanced breast cancer. This success has led to continued pursuit of targeting other CDKs. One cha...

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Bibliographic Details
Main Author:	Mark Klein
Format:	Article
Language:	English
Published:	MDPI AG 2023-03-01
Series:	Pharmaceuticals
Subjects:	protein-protein interaction inhibitor cyclin-dependent kinase cyclin neoplasm
Online Access:	https://www.mdpi.com/1424-8247/16/4/519

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