Identification of RNase L-Dependent, 3′-End-Modified, Viral Small RNAs in Sindbis Virus-Infected Mammalian Cells

ABSTRACT Small RNAs play a critical role in host-pathogen interaction. Indeed, small RNA-mediated silencing or RNA interference (RNAi) is one of the earliest forms of antiviral immunity. Although it represents the main defense system against viruses in many organisms, the antiviral role of RNAi has...

Full description

Bibliographic Details
Main Authors: Erika Girardi, Béatrice Chane-Woon-Ming, Mélanie Messmer, Pasi Kaukinen, Sébastien Pfeffer
Format: Article
Language:English
Published: American Society for Microbiology 2013-12-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00698-13