Imaging Gene Expression in Regional Brain Ischemia in Vivo with a Targeted [In]-Antisense Radiopharmaceutical
The gene encoding glial fibrillary acidic protein (GFAP) is down-regulated 24 hr after reversible brain ischemia, such as with a middle cerebral artery occlusion (MCAO). The in vivo imaging of decreased GFAP gene expression in cerebral ischemia was examined in the present studies using a targeted pe...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2004-10-01
|
Series: | Molecular Imaging |
Online Access: | https://doi.org/10.1162/15353500200404145 |