C/EBPβ/AEP is age-dependently activated in Parkinson’s disease and mediates α-synuclein in the gut and brain

C/EBPβ/AEP is age-dependently activated in Parkinson’s disease and mediates α-synuclein in the gut and brain

Abstract Parkinson’s disease (PD) is the most common neurodegenerative motor disorder, and its pathologic hallmarks include extensive dopaminergic neuronal degeneration in the Substantia nigra associated with Lewy bodies, predominantly consisting of phosphorylated and truncated α-Synuclein (α-Syn)....

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Bibliographic Details
Main Authors: Hualong Wang, Guiqin Chen, Eun Hee Ahn, Yiyuan Xia, Seong Su Kang, Xia Liu, Chang Liu, Ming-Hu Han, Shengdi Chen, Keqiang Ye
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-022-00430-8

Internet

https://doi.org/10.1038/s41531-022-00430-8

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