Convenient Auto-Processing Vector Based on Bamboo Mosaic Virus for Presentation of Antigens Through Enzymatic Coupling

Convenient Auto-Processing Vector Based on Bamboo Mosaic Virus for Presentation of Antigens Through Enzymatic Coupling

We have developed a new binary epitope-presenting CVP platform based on bamboo mosaic virus (BaMV) by using the sortase A (SrtA)-mediated ligation technology. The reconstructed BaMV genome harbors two modifications: 1) a coat protein (CP) with N-terminal extension of the tobacco etch virus (TEV) pro...

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Bibliographic Details
Main Authors: Ming-Hao Yang, Chung-Chi Hu, Chi-Hzeng Wong, Jian-Jong Liang, Hui-Ying Ko, Meng-Hsun He, Yi-Ling Lin, Na-Sheng Lin, Yau-Heiu Hsu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
Bamboo mosaic virus (BaMV)
chimeric virus particle (CVP)
nanoparticle
virus-like particle (VLP)
antigen presentation platform
Tobacco etch virus protease (TEVp)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.739837/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.739837/full

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