Extrachromosomal Circular DNA: A New Target in Cancer

Extrachromosomal Circular DNA: A New Target in Cancer

Genomic instability and amplification are intrinsically important traits determining the development and heterogeneity of tumors. The role of extrachromosomal circular DNA (eccDNA) in tumors has recently been highlighted. EccDNAs are unique genetic materials located off the chromosomal DNA. They hav...

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Bibliographic Details
Main Authors: Pan Wu, Yuhang Liu, Ruijia Zhou, Lingyun Liu, Hongli Zeng, Fang Xiong, Shanshan Zhang, Zhaojian Gong, Wenling Zhang, Can Guo, Fuyan Wang, Ming Zhou, Xuyu Zu, Zhaoyang Zeng, Yong Li, Guiyuan Li, He Huang, Wei Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
eccDNA
double-minute
cancer
heterogeneity
tumor biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.814504/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.814504/full

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