Leukocyte Expression of Type 1 and Type 2 Purinergic Receptors and Pro-Inflammatory Cytokines during Total Sleep Deprivation and/or Sleep Extension in Healthy Subjects

Leukocyte Expression of Type 1 and Type 2 Purinergic Receptors and Pro-Inflammatory Cytokines during Total Sleep Deprivation and/or Sleep Extension in Healthy Subjects

The purinergic type P1 (adenosine A1 and A2A) receptors and the type P2 (X7) receptor have been suggested to mediate physiological effects of adenosine and adenosine triphosphate on sleep. We aimed to determine gene expression of A1R (receptor), A2AR, and P2RX7 in leukocytes of healthy subjects duri...

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Bibliographic Details
Main Authors: Mounir Chennaoui, Pierrick J. Arnal, Catherine Drogou, Damien Leger, Fabien Sauvet, Danielle Gomez-Merino
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Neuroscience
Subjects:
sleep deprivation
adenosine and purinergic receptors
gene expression
leukocytes
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00240/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2017.00240/full

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