Multifunctional interaction of CihC/FbpC orthologs of relapsing fever spirochetes with host-derived proteins involved in adhesion, fibrinolysis, and complement evasion

Multifunctional interaction of CihC/FbpC orthologs of relapsing fever spirochetes with host-derived proteins involved in adhesion, fibrinolysis, and complement evasion

IntroductionRelapsing fever (RF) remains a neglected human disease that is caused by a number of diverse pathogenic Borrelia (B.) species. Characterized by high cell densities in human blood, relapsing fever spirochetes have developed plentiful strategies to avoid recognition by the host defense mec...

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Bibliographic Details
Main Authors: Ann-Sophie Damm, Flavia Reyer, Luisa Langhoff, Yi-Pin Lin, Franco Harald Falcone, Peter Kraiczy
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
relapsing fever
spirochetes
Borrelia
complement
immune evasion
host cell interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1390468/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1390468/full

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