Deciphering the role of extrachromosomal circular DNA in adipose stem cells from old and young donors

Abstract Background The functional impairment of adipose stem cells (ASCs) during aging limits their clinical transformation. Studies have shown that extrachromosomal circular DNAs (eccDNAs) are associated with tumor progression and cell aging, but the roles of eccDNAs in ASCs remain unknown. Method...

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Bibliographic Details
Main Authors: Sen Ren, Du Wu, Xiaoyong Shen, Qian Wu, Chengcheng Li, Hewei Xiong, Zhongwei Xiong, Rui Gong, Zheng Liu, Wei Wang, Jincao Chen
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-023-03575-2