Mitochondria-Targeted Lipid Nanoparticles Loaded with Rotenone as a New Approach for the Treatment of Oncological Diseases

Mitochondria-Targeted Lipid Nanoparticles Loaded with Rotenone as a New Approach for the Treatment of Oncological Diseases

This research is based on the concept that mitochondria are a promising target for anticancer therapy, including thatassociated with the use of oxidative phosphorylation blockers (mitochondrial poisons). Liposomes based on L-α-phosphatidylcholine (PC) and cholesterol (Chol) modified with cationic su...

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Bibliographic Details
Main Authors: Leysan Vasileva, Gulnara Gaynanova, Darya Kuznetsova, Farida Valeeva, Anna Lyubina, Syumbelya Amerhanova, Alexandra Voloshina, Guzel Sibgatullina, Dmitry Samigullin, Konstantin Petrov, Lucia Zakharova
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Molecules
Subjects:
mitochondria
cationic surfactant
triphenylphosphonium
imidazolium
liposome
rotenone
Online Access:https://www.mdpi.com/1420-3049/28/20/7229

Internet

https://www.mdpi.com/1420-3049/28/20/7229

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