Trends and prospects in mitochondrial genome editing

Abstract Mitochondria are of fundamental importance in programmed cell death, cellular metabolism, and intracellular calcium concentration modulation, and inheritable mitochondrial disorders via mitochondrial DNA (mtDNA) mutation cause several diseases in various organs and systems. Nevertheless, mt...

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Bibliographic Details
Main Authors: Hong Thi Lam Phan, Hyunji Lee, Kyoungmi Kim
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-00973-7