A comparison of assays for accurate copy number measurement of the low-affinity Fc gamma receptor genes FCGR3A and FCGR3B.

A comparison of assays for accurate copy number measurement of the low-affinity Fc gamma receptor genes FCGR3A and FCGR3B.

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The FCGR3 locus encoding the low affinity activating receptor FcγRIII, plays a vital role in immunity triggered by cellular effector and regulatory functions. Copy number of the genes FCGR3A and FCGR3B has previously been reported to affect susceptibility to several autoimmune diseases and chronic i...

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Bibliographic Details
Main Authors: Umi Shakina Haridan, Umairah Mokhtar, Lee R Machado, Abu Thalhah Abdul Aziz, Rafidah Hanim Shueb, Masliza Zaid, Benedict Sim, Mahiran Mustafa, Nik Khairudin Nik Yusof, Christopher K C Lee, Suhaili Abu Bakar, Sazaly AbuBakar, Edward J Hollox, Hoh Boon Peng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4297192?pdf=render

Internet

http://europepmc.org/articles/PMC4297192?pdf=render

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