Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution

Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution

The glucagon-like peptide-1 receptor (GLP1R) is a broadly expressed target of peptide hormones with essential roles in energy and glucose homeostasis, as well as of the blockbuster weight-loss drugs semaglutide and liraglutide. Despite its large clinical relevance, tools to investigate the precise a...

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Bibliographic Details
Main Authors: Loïc Duffet, Elyse T Williams, Andrea Gresch, Simin Chen, Musadiq A Bhat, Dietmar Benke, Nina Hartrampf, Tommaso Patriarchi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-06-01
Series:eLife
Subjects:
GLP1R
genetically encoded sensor
fluorescence
neuropeptide
photocage
Online Access:https://elifesciences.org/articles/86628

Internet

https://elifesciences.org/articles/86628

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