Presynaptic GABAB receptors functionally uncouple somatostatin interneurons from the active hippocampal network

Presynaptic GABAB receptors functionally uncouple somatostatin interneurons from the active hippocampal network

Information processing in cortical neuronal networks relies on properly balanced excitatory and inhibitory neurotransmission. A ubiquitous motif for maintaining this balance is the somatostatin interneuron (SOM-IN) feedback microcircuit. Here, we investigated the modulation of this microcircuit by p...

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Bibliographic Details
Main Authors: Sam A Booker, Harumi Harada, Claudio Elgueta, Julia Bank, Marlene Bartos, Akos Kulik, Imre Vida
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-02-01
Series:eLife
Subjects:
hippocampus
feedback inhibition
synaptic transmission
GABAergic interneurons
network activity
Online Access:https://elifesciences.org/articles/51156

Internet

https://elifesciences.org/articles/51156

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