Angiotensin II Promotes SARS-CoV-2 Infection via Upregulation of ACE2 in Human Bronchial Cells

Angiotensin II Promotes SARS-CoV-2 Infection via Upregulation of ACE2 in Human Bronchial Cells

Blockers of the renin-angiotensin system (RAS) have been reported to increase the angiotensin converting enzyme (ACE)2, the cellular receptor of SARS-CoV-2, and thus the risk and course of COVID-19. Therefore, we investigated if angiotensin (Ang) II and RAS blockers affected ACE2 expression and SARS...

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Bibliographic Details
Main Authors: Ilaria Caputo, Brasilina Caroccia, Ilaria Frasson, Elena Poggio, Stefania Zamberlan, Margherita Morpurgo, Teresa M. Seccia, Tito Calì, Marisa Brini, Sara N. Richter, Gian Paolo Rossi
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
angiotensin-converting enzyme 2
angiotensin II
severe acute respiratory syndrome coronavirus 2
angiotensin-converting enzyme inhibitor
angiotensin receptor blocker
COVID-19
Online Access:https://www.mdpi.com/1422-0067/23/9/5125

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https://www.mdpi.com/1422-0067/23/9/5125

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