Calcium Transient and Sodium-Calcium Exchange Current in Human versus Rabbit Sinoatrial Node Pacemaker Cells

There is an ongoing debate on the mechanism underlying the pacemaker activity of sinoatrial node (SAN) cells, focusing on the relative importance of the “membrane clock” and the “Ca2+ clock” in the generation of the small net membrane current that depolarizes the cell towards the action potential th...

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Detalles Bibliográficos
Autores principales: Arie O. Verkerk, Marcel M. G. J. van Borren, Ronald Wilders
Formato: Artículo
Lenguaje:English
Publicado: Wiley 2013-01-01
Colección:The Scientific World Journal
Acceso en línea:http://dx.doi.org/10.1155/2013/507872