Pushing the performance of image scanning microscopy to its limits with maximum likelihood reconstruction

Fast and sensitive detector arrays make Image Scanning Microscopy (ISM) the natural successor of confocal microscopy. Indeed, ISM enables super-resolution at an excellent signal-to-noise ratio. Optimizing photon collection requires large detectors and so more out-of-focus light is collected. Nonethe...

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Bibliographic Details
Main Authors: Garré Giacomo, Zunino Alessandro, Fersini Francesco, Vicidomini Giuseppe
Format: Article
Language:English
Published: EDP Sciences 2023-01-01
Series:EPJ Web of Conferences
Online Access:https://www.epj-conferences.org/articles/epjconf/pdf/2023/13/epjconf_eosam2023_03001.pdf