BISMA - Fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequences

<p>Abstract</p> <p>Background</p> <p>Bisulfite sequencing is a popular method to analyze DNA methylation patterns at high resolution. A region of interest is targeted by PCR and about 20-50 subcloned DNA molecules are usually analyzed, to determine the methylation statu...

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Bibliographic Details
Main Authors: Reinhardt Richard, Zhang Yingying, Rohde Christian, Jeltsch Albert
Format: Article
Language:English
Published: BMC 2010-05-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/230