Functional Maturation of Human Stem Cell-Derived Neurons in Long-Term Cultures.
Differentiated neurons can be rapidly acquired, within days, by inducing stem cells to express neurogenic transcription factors. We developed a protocol to maintain long-term cultures of human neurons, called iNGNs, which are obtained by inducing Neurogenin-1 and Neurogenin-2 expression in induced p...
Main Authors: | Rebecca S Lam, Felix M Töpfer, Phillip G Wood, Volker Busskamp, Ernst Bamberg |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5215418?pdf=render |
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