Albumin-Binding PSMA Radioligands: Impact of Minimal Structural Changes on the Tissue Distribution Profile

The concept of using ibuprofen as an albumin-binding entity was recently demonstrated by the development of [<sup>177</sup>Lu]Lu-Ibu-PSMA-01. In the present study, we designed a novel ibuprofen-containing radioligand (Ibu-PSMA-02) with subtle structural changes regarding the linker entit...

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Bibliographic Details
Main Authors: Luisa M. Deberle, Viviane J. Tschan, Francesca Borgna, Fan Sozzi-Guo, Peter Bernhardt, Roger Schibli, Cristina Müller
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/11/2542