Cellular and circuit diversity determines the impact of endogenous opioids in the descending pain modulatory pathway
The descending pain modulatory pathway exerts important bidirectional control of nociceptive inputs to dampen and/or facilitate the perception of pain. The ventrolateral periaqueductal gray (vlPAG) integrates inputs from many regions associated with the processing of nociceptive, cognitive, and affe...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-08-01
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Series: | Frontiers in Systems Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnsys.2022.963812/full |