Self-Assembling Injectable Hydrogel for Controlled Drug Delivery of Antimuscular Atrophy Drug Tilorone

Self-Assembling Injectable Hydrogel for Controlled Drug Delivery of Antimuscular Atrophy Drug Tilorone

A two-component injectable hydrogel was suitably prepared for the encapsulation and prolonged release of tilorone which is an antimuscular atrophy drug. The rapid (7–45 s, depending on the polymer concentration) in situ solidifications of the hydrogel were evoked by the evolving Schiff-base bonds be...

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Bibliographic Details
Main Authors: Mohamed M. Abdelghafour, Ágota Deák, Tamás Kiss, Mária Budai-Szűcs, Gábor Katona, Rita Ambrus, Bálint Lőrinczi, Anikó Keller-Pintér, István Szatmári, Diána Szabó, László Rovó, László Janovák
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceutics
Subjects:
thiolated chitosan
modified PVA
tilorone
injectable self-assembled hydrogel
mucoadhesive hydrogel
prolonging drug release
Online Access:https://www.mdpi.com/1999-4923/14/12/2723

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https://www.mdpi.com/1999-4923/14/12/2723

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