Lower HOMA-β values are detected among individuals with variant of E23K polymorphism of potassium inwardly-rectifying channel, subfamily J, member 11 (KCNJ11) gene

Lower HOMA-β values are detected among individuals with variant of E23K polymorphism of potassium inwardly-rectifying channel, subfamily J, member 11 (KCNJ11) gene

Background: Type 2 Diabetes Mellitus (T2DM) is a multifactorial disease involving both genetic and also environmental factors. Potassium inwardly-rectifying channel, subfamily J, member 11 (KCNJ11) gene, an ATP-sensitive potassium channel-coding gene, contributes to insulin secretion. Objectives: Th...

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Bibliographic Details
Main Authors: Raden Sunita, Ahmad Hamim Sadewa, Arta Farmawati
Format: Article
Language:English
Published: SpringerOpen 2015-07-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
T2DM
E23K polymorphism of KCNJ11
HOMA-β
Individuals with family history of T2DM
Individuals without family history of T2DM
Online Access:http://www.sciencedirect.com/science/article/pii/S1110863015000403

Internet

http://www.sciencedirect.com/science/article/pii/S1110863015000403

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