Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy

Determination of apical tension, fluidity, and intercellular adhesive forces in an epithelial monolayer are currently disruptive. Here the authors present a method using acoustic force microscopy to measure changes in these parameters upon tight junction structural alterations in a MDCK monolayer.

Bibliographic Details
Main Authors: Alexander X. Cartagena-Rivera, Christina M. Van Itallie, James M. Anderson, Richard S. Chadwick
Format: Article
Language:English
Published: Nature Portfolio 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01145-8