Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy
Determination of apical tension, fluidity, and intercellular adhesive forces in an epithelial monolayer are currently disruptive. Here the authors present a method using acoustic force microscopy to measure changes in these parameters upon tight junction structural alterations in a MDCK monolayer.
Main Authors: | Alexander X. Cartagena-Rivera, Christina M. Van Itallie, James M. Anderson, Richard S. Chadwick |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-01145-8 |
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