Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2 T-type voltage-gated calcium channels and Ca2+ influxResearch in context

Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2 T-type voltage-gated calcium channels and Ca2+ influxResearch in context

Background: Administration of amplitude modulated 27·12 MHz radiofrequency electromagnetic fields (AM RF EMF) by means of a spoon-shaped applicator placed on the patient's tongue is a newly approved treatment for advanced hepatocellular carcinoma (HCC). The mechanism of action of tumour-specifi...

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Bibliographic Details
Main Authors: Hugo Jimenez, Minghui Wang, Jacquelyn W. Zimmerman, Michael J. Pennison, Sambad Sharma, Trevor Surratt, Zhi-Xiang Xu, Ivan Brezovich, Devin Absher, Richard M. Myers, Barry DeYoung, David L. Caudell, Dongquan Chen, Hui-Wen Lo, Hui-Kuan Lin, Dwayne W. Godwin, Michael Olivier, Anand Ghanekar, Kui Chen, Lance D. Miller, Yijian Gong, Myles Capstick, Ralph B. D'Agostino, Jr, Reginald Munden, Philippe Merle, Alexandre Barbault, Arthur W. Blackstock, Herbert L. Bonkovsky, Guang-Yu Yang, Guangxu Jin, Liang Liu, Wei Zhang, Kounosuke Watabe, Carl F. Blackman, Boris C. Pasche
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419303421

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http://www.sciencedirect.com/science/article/pii/S2352396419303421

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