Transcriptional landscape associated with TNBC resistance to neoadjuvant chemotherapy revealed by single-cell RNA-seq

Transcriptional landscape associated with TNBC resistance to neoadjuvant chemotherapy revealed by single-cell RNA-seq

Triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy (NAC) represents a major clinical challenge; therefore, delineating tumor heterogeneity can provide novel insight into resistance mechanisms and potential therapeutic targets. Herein, we identified the transcriptional landsc...

Full description

Bibliographic Details
Main Authors: Radhakrishnan Vishnubalaji, Nehad M. Alajez
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Molecular Therapy: Oncolytics
Subjects:
triple-negative breast cancer
TNBC
neoadjuvant chemotherapy
NAC
resistance
single cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770521001297

Internet

http://www.sciencedirect.com/science/article/pii/S2372770521001297

Similar Items