β-thalassemias: paradigmatic diseases for scientific discoveries and development of innovative therapies
β-thalassemias are monogenic disorders characterized by defective synthesis of the β-globin chain, one of the major components of adult hemoglobin. A large number of mutations in the β-globin gene or its regulatory elements have been associated with β-thalassemias. Due to the complexity of the regul...
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| Format: | Article |
| Language: | English |
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Ferrata Storti Foundation
2015-04-01
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| Series: | Haematologica |
| Online Access: | https://haematologica.org/article/view/7333 |