Effects of GSTM1 in rheumatoid arthritis; results from the Swedish EIRA study.

OBJECTIVE: Glutathione-S-transferases (GSTs) play an important role in tobacco smoke detoxification, interestingly approximately 50% of individuals in most human populations lack the gene GSTM1 due to copy number variation (CNV). We aimed to investigate GSTM1 CNV in Rheumatoid Arthritis (RA) in rela...

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Bibliographic Details
Main Authors: Emeli Lundström, Toinette Hartshorne, Kelly Li, Staffan Lindblad, Marius C Wick, Camilla Bengtsson, Lars Alfredsson, Lars Klareskog, Leonid Padyukov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3062563?pdf=render