Whole-exome sequencing analysis identifies distinct mutational profile and novel prognostic biomarkers in primary gastrointestinal diffuse large B-cell lymphoma

Whole-exome sequencing analysis identifies distinct mutational profile and novel prognostic biomarkers in primary gastrointestinal diffuse large B-cell lymphoma

Abstract Background Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive non-Hodgkin lymphoma, and about 10% of DLBCL cases primarily occur in the gastrointestinal tract. Previous reports have revealed that primary gastrointestinal-DLBCL (pGI-DLBCL) harbors different genetic mutations...

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Bibliographic Details
Main Authors: Shan-Shan Li, Xiao-Hui Zhai, Hai-Ling Liu, Ting-Zhi Liu, Tai-Yuan Cao, Dong-Mei Chen, Le-Xin Xiao, Xiao-Qin Gan, Ke Cheng, Wan-Jia Hong, Yan Huang, Yi-Fan Lian, Jian Xiao
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Experimental Hematology & Oncology
Subjects:
Whole-exome sequencing/WES
Diffuse large B-cell lymphoma/DLBCL
Gastrointestinal tract/GI tract
Mutation profile
IGLL5
LRP1B
Online Access:https://doi.org/10.1186/s40164-022-00325-7

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https://doi.org/10.1186/s40164-022-00325-7

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